Prednisone (PRED ni sone) is used to treat conditions such as arthritis, blood disorders, breathing problems, certain cancers, eye problems, immune system diseases, and skin diseases.
Take this medication by mouth with food to prevent stomach upset. If you are prescribed only one dose per day, take it in the morning. If you are taking this medication every other day or on another schedule besides a daily one, it may help to mark your calendar with a reminder. Take this medication exactly as directed by your doctor. Follow the dosing schedule carefully. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped.
Stomach upset, headache, dizziness, trouble sleeping, or weight gain may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: black stools, bone pain (fracture), "coffee-ground" vomit, easy bruising/bleeding, heartburn, increased thirst and urination, irregular/fast/pounding heartbeat, menstrual period changes, mental/mood changes, muscle weakness/pain, persistent weight gain, puffy face, seizures, signs of infection (e.g., fever, persistent sore throat), slow-healing wounds, stomach/abdominal pain, swelling of the feet/ankles, thinning skin, trouble breathing, unusual hair growth, unusual skin growths, vision changes. A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor.
Before taking Prednisone, tell your doctor if you are allergic to it; or if you have any other allergies. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor if you have: untreated active fungal infections. Before using this medication, tell your doctor your medical history, especially of: bleeding problems, history of blood clots, bone loss (osteoporosis), certain nerve/muscle disease (myasthenia gravis), diabetes, eye diseases (e.g., ocular herpes infection, cataracts, glaucoma), heart problems (congestive heart failure), high blood pressure, kidney disease, mental/mood conditions, other infections (e.g., tuberculosis, threadworm), severe liver disease (cirrhosis), stomach/intestinal problems (e.g., ulcer, ulcerative colitis, diverticulitis), underactive thyroid. Make sure your doctors know that you are taking this medication or have used it in the past. This medication may mask signs of infection or put you at greater risk of developing very serious (rarely fatal) infections. Report any injuries or signs of infection (e.g., persistent sore throat/fever/cough, pain during urination, muscle aches) that occur during treatment. If your body is under severe stress due to major infection, surgery, or injury, your dose may need to be adjusted upward if you are using a very low dose of Prednisone for a long time. Your body may not be able to make enough natural steroids. If you have stopped taking this drug within the past 12 months, consult your doctor. You may need to start taking it again if your body is under severe stress. Tell your doctor immediately if any of the following side effects occur when your body is under severe stress: unusual weakness, sudden weight loss, dizziness. Tell your doctor if you are scheduling surgery. Avoid exposure to chickenpox or measles infection while taking this medication. If you are exposed to these infections, seek immediate medical attention. If you have a history of ulcers or take large doses of aspirin or other arthritis medication, limit alcoholic beverages while taking this drug. Alcohol may increase the risk of stomach/intestinal bleeding. If you have diabetes, this drug may increase your blood sugar levels. Check your blood (or urine) glucose level frequently, as directed by your doctor. Promptly report any abnormal results as directed. Your medicine, exercise plan, or diet may need to be adjusted. This drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. This medication is not recommended for use during pregnancy due to possible fetal harm. Consult your doctor for more details. This medication passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.
This drug should not be used with the following medications because very serious interactions may occur: Aldesleukin, Mifepristone. If you are currently using any of these medications, tell your doctor before starting Prednisone. Before using this medication, tell your doctor of all prescription and nonprescription/herbal products you may use, especially of: large doses of aspirin and aspirin-like drugs (salicylates), birth control pills, "blood thinners" (e.g., warfarin), estrogens, nonsteroidal anti-inflammatory drugs (NSAIDs such as indomethacin, ibuprofen), drugs which decrease blood potassium levels (e.g., amphotericin B, "water pills" such as hydrochlorothiazide and furosemide), drugs which affect certain liver enzymes (CYP 3A4 substrates, inhibitors and inducers such as azole antifungals, macrolide antibiotics, rifamycins, certain anti-seizure medications). Do not have any vaccinations, immunizations or skin tests while you are using this drug unless specifically directed by your doctor. Live vaccines may cause serious complications (e.g., infection) if given while you are taking this medication. Consult your doctor for details. Low-dose aspirin, as prescribed by your doctor for heart attack or stroke prevention (usually these dosages are 81-325 mg per day), should be continued. Consult your doctor for more details. Do not start or stop any medicine without doctor approval.
If you are taking this medication daily and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Ask your doctor ahead of time what you should do if you are taking this medication every other day or on another schedule besides a daily one, and you miss a dose.
Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.