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Nizoral (ketoconazole) is an antifungal medication. Fungi are organisms normally found on the skin and in moist areas of the body. When the skin is injured or chronically moistened, or normal bacteria flora of the body are altered due to prolonged antibiotic treatment, fungus can proliferate to cause inflammation of the skin or moist body areas.
Nizoral may also be marketed as: Extina, Fungoral, Ketoconazole, Ketoderm.
*Nizoral® is a registered trademark of Ortho-McNeil Pharmaceutical.
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Ketoconazole is an azole antifungal. It kills sensitive fungi by interfering with the formation of the fungal cell membrane.
Ketoconazole should be avoided by patients with liver dysfunction. Signs of liver problems include unusual fatigue, loss of appetite, nausea and vomiting, yellowing of the skin (jaundice), dark urine, and pale stools. Development of these symptoms while taking ketoconazole should be reported to the physician.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
·1 dizziness, fainting, fast or pounding heartbeat;
·2 easy bruising or bleeding, unusual weakness;
·3 numbness or tingly feeling;
·4 severe depression, confusion, or thoughts of hurting yourself; or
·5 Nausea, stomach pain, low fever, loss of appetite, weakness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
·1 mild nausea, vomiting, or stomach pain;
·2 mild itching or skin rash;
·5 breast swelling; or
·6 Impotence or loss of interest in sex.
·1 acetaminophen (Tylenol);
·2 cyclosporine (Gengraf, Sandimmune, Neoral);
·3 digoxin (digitalis, Lanoxin);
·4 tacrolimus (Prograf);
·5 loratadine (Alavert, Claritin, Tavist ND);
·6 methylprednisolone (Medrol);
·7 phenytoin (Dilantin);
·8 rifampin (Rifadin, Rifater, Rifamate, Rimactane);
·9 diabetes medication you take by mouth;
·10 a sedative such as midazolam (Versed);
·11 a blood thinner such as warfarin (Coumadin);
·12 cancer medications;
·13 birth control pills or hormone replacement therapy;
·14 methotrexate (Rheumatrex, Trexall);
·15 cholesterol medications such as niacin (Advicor), atorvastatin (Lipitor), lovastatin (Altocor, Mevacor), simvastatin (Zocor), and others; or
·16 medications to treat HIV or AIDS.