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Seroflo (Salmeterol and Fluticasone) is given to patients suffering from asthma to help prevent asthma attacks. This medication is also used to help prevent shortness of breath and wheezing occurring as a result of chronic obstructive pulmonary disease. It works by helping the muscles of the airways to relax, which helps to make breathing easier.
*Seroflo® is manufactured by Cipla Ltd.
Each Seroflo inhaler contains 120 doses of 25mcg/250mcg of Salmeterol and Fluticasone
Seroflo 120 Metered Doses of 25mcg/250mcg Inhaler
Fluticasone is a steroid. It prevents the release of substances in the body that cause inflammation. Salmeterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing.
Fluticasone and salmeterol inhalation is used to prevent asthma attacks. It is also used to prevent flare-ups or worsening of chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis and/or emphysema.
Do not use fluticasone and salmeterol inhalation to treat an asthma attack that has already begun. It will not work fast enough. Use only a fast-acting inhalation medication.
Seroflo is a powder form of fluticasone and salmeterol that comes with a special inhaler device pre-loaded with blister packs containing measured doses of the medicine. The device opens and loads a blister each time you use the inhaler. This device is not to be used with a spacer.
Shake the Seroflo inhaler for at least 5 seconds before each spray.
Use all of your medications as directed by your doctor. Talk with your doctor if your medications do not seem to work as well in treating or preventing attacks. Do not change your doses or medication schedule without advice from your doctor.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- bronchospasm (wheezing, chest tightness, trouble breathing);
- fast or uneven heart beats, restless feeling, tremor;
- fever, chills, stabbing chest pain, cough with yellow or green mucus;
- blurred vision, eye pain, or seeing halos around lights;
- white patches or sores inside your mouth or on your lips; or
- worsening asthma symptoms.
Less serious side effects include:
- headache, dizziness;
- nausea, vomiting, diarrhea;
- dry mouth, nose, or throat;
- stuffy nose, sinus pain, cough, sore throat; or
- hoarseness or deepened voice.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Do not use this medication if you are allergic to fluticasone (Flonase, Flovent), salmeterol (Serevent), or milk proteins, or if you are having an asthma attack or severe COPD symptoms.
To make sure you can safely use fluticasone and salmeterol, tell your doctor if you have any of these other conditions:
- a food or drug allergy;
- heart disease or high blood pressure;
- epilepsy or other seizure disorder;
- any type of infection;
- a weak immune system;
- a thyroid disorder; or
- liver disease.
FDA pregnancy category C. It is not known whether fluticasone and salmeterol is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
Fluticasone and salmeterol inhalation can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.
Do not give this medication to a child younger than 4 years old.
Long-term use of steroids may lead to bone loss (osteoporosis), especially if you smoke, if you do not exercise, if you do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis.
Tell your doctor about all other medicines you use, especially:
- amiodarone (Cordarone);
- a diuretic or "water pill";
- HIV medicines such as atazanavir (Reyataz), ritonavir (Norvir), indinavir (Crixivan), nelfinavir (Viracept), or saquinavir (Invirase);
- an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam);
- an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), desipramine (Norpramin), fluoxetine (Prozac), nefazodone, or imipramine (Tofranil);
- antibiotics such as clarithromycin (Biaxin) or telithromycin (Ketek);
- antifungal medications such as ketoconazole (Nizoral) or itraconazole (Sporanox); or
- a beta-blocker such as atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), and others.
This list is not complete and other drugs may interact with fluticasone and salmeterol inhalation. Tell your doctor about all medications you use.
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
Store at room temperature away from moisture and heat. Keep the canister away from high heat, such as open flame or in a car on a hot day. The canister may explode if it gets too hot.